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Skin Tumor


Seborrhoeic warts appear on the skin. This is caused by excessive exposure of skin to sun rays. If not treated in time, leads to skin cancer. It can be removed surgically.

UV-B is a complete carcinogen, meaning that it can function as both an initiator and a promoter, leading to tumor induction.

Exposure to a tumor initiator is believed to be a necessary but not sufficient step in the malignant process, since initiated skin cells not exposed to tumor promoters do not generally develop tumors. The second stage in tumor development is promotion, a multistep process whereby initiated cells are exposed to chemical and physical agents that evoke epigenetic changes that culminate in the clonal expansion of initiated cells and cause the development, over a period of weeks to months, of benign growths known as papillomas.

The relationship of sun exposure to melanoma is less clear-cut, but suggestive evidence supports an association. Melanomas occasionally develop by the teenage years, indicating that the latent period for tumor growth is less than that of nonmelanoma skin cancer.

It is known that UV-induced tumors in murine skin are antigenic and are rapidly rejected when transplanted into normal syngeneic animals. If the tumors are transplanted into animals previously exposed to subcarcinogenic doses of UV-B, they are not rejected and instead grow progressively in the recipients. This failure of irradiated animals to reject the transplanted tumors is due to the development of T suppressor cells that prevent the rejection response. While the mechanism of suppression of tumor rejection is unknown, such a response might be a critical determinant of cancer risk in human skin.

 

Skin Diseases

Eczema
Atopic Eczema
Acanthosis Nigricans
Skin Tumor
Skin Cancers
Ehlers Danlos Syndrome
Eye Stye
Pyoderma faciale
Rosacea
Sarcoid
Seborrhoeic dermatitis
Solar (senile) comedones
Steroid acne
Steroid rosacea
Vitiligo
Granuloma faciale
Jessner's lymphocytic infiltrate
Perioral Dermatitis
Photosensitivity
Poikiloderma of Civatte
Pseudofolliculitis barbae (shaving bumps)
Psoriasis
Actinic Keratoses
Ageing skin
Angioedema
Cutaneous lupus erythematosus
Chloasma (melasma)
Dermatitis (eczema)
Dermatomyositis

Atopic Dermatitis
Acne Treatment
Athlete's Foot
Blackheads
Bullous Pemphigoid
Chilblains
Chapped Lips
Dark Circles
Acrochordons
Fordyce's Condition
Granuloma Annulare
Hidradenitis Suppurativa
Hyperhidrosis
Herpes Simplex
Herpes Zoster
Impetigo
Intertrigo
Keratosis Pilaris
Keratoacanthoma
Keloids
Lichen Striatus
Lichen Sclerosus
Mastocytosis
Molluscum Contagiosum
Malignant Melanoma
Onychomycosis
Pruritis
Pityriasis Alba
Pityriasis Rosea
Pompholyx
Sunburn
Telogen Effluvium
Vulvodynia
Xerosis

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